Next week's climax will focus on the U.S. embassy move to Jerusalem, taking place on Monday, and commemorating Nakba (catastrophe) day, when Palestinians mark the 70th anniversary of the establishment of the state of Israel and the birth of the Palestinian refugee problem.
At least one Palestinian was killed and more than 400 wounded from live Israeli fire and tear gas on Friday, as some 15,000 Palestinians participated in protests along the Gaza border for the seventh consecutive weekend.
The protests also took place at the contact points in different cities, including the northern entrance of Bethlehem and Ramallah.
Demonstrations are also expected in Jerusalem and the West Bank, where Palestinians have not for the most part joined in the Gaza campaign.
No Israelis casualties have been reported, although several fires have erupted along the border after kites carrying improvised incendiary devices made their way into Israel.
A Palestinian man is rushed to an ambulance at the border fence.
It said seven of the 49 protesters hit by Israeli fire were in a serious condition and that dozens of others were overcome by tear gas inhalation.
Palestinian protesters carry an injured man during clashes with Israeli troops on the Gaza-Israel border east of Gaza City, on May 11, 2018.
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The area was quickly engulfed in thick black smoke from the burning tires.
Almost 150 other Palestinians were shot by Israeli forces during the demonstrations, the ministry said.
Israeli forces have drawn worldwide censure for using live fire against the protesters, most of whom appeared unarmed and did not seem to present any immediate threat to the lives of the soldiers.
In recent weeks, soldiers have fired from behind sand berms.
Numerous protesters are peaceful and Israeli officials say they only target protesters who threaten the border.
Separately, the border with Egypt, the only country apart from Israel with which Gaza shares a border, is set to open its crossing for four days starting on Saturday, the Palestinian embassy in Cairo said. The demonstrations have been organized by Gaza's Hamas rulers, but are fuelled by despair among the territory's 2 million people.
Holding Palestinian flags and banners, the protesters were chanting "Free Palestine", "Freedom Now" and "End Occupation" slogans.