Republicans have a 51-49 majority in the Senate.
Of the four lawmakers who had not revealed their decisions until Friday - all moderates - Republican Sens.
The Senate vote was 50-48.Only one Democrat, Joe Manchin of West Virginia, joined Republicans in backing Kavanaugh.
Despite deciding against the nominee on Friday, she told reporters afterwards she has still not made up her mind on the confirmation vote, according to Reuters news agency. An appellate court judge on the District of Columbia circuit for the past 12 years, he pushed for the Senate vote as hard as Republican leaders - not just to reach this capstone of his legal career, but in fighting to clear his name. But on the other hand, Murkowski's bombshell gives Collins some cover should she vote "no". She doesn't want the process to drag on into the next Congress should Democrats end up winning control on Capitol Hill.
Vice President Mike Pence planned to be available Saturday in case his tie-breaking vote was needed, which now seems unlikely.
Brett Kavanaugh's Supreme Court seat looks all but confirmed after he won the backing of key senators despite an FBI investigation into sexual assault allegations.
Christine Blasey Ford's sister-in-law said Sens.
The debate sparked smoldering resentment by partisans on both sides, on and off the Senate floor.
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More than 300 protestors - including the comedian Amy Schumer and model Emily Ratajkowski - were arrested as they made desperate final appeals to senators as they arrived at the US Capitol in Washington.
On the Senate floor, lawmakers' comments underscored the lingering bitterness.
Emily Grossi, a protester from Maryland, accused Flake of locking a door on democracy, saying his was the only office she encountered Friday that was not open for constituents to voice their concerns.
The US Senate has narrowly advanced President Donald Trump's Supreme Court nominee Brett Kavanaugh's nomination to a final vote. Dianne Feinstein of California, but the allegation leaked.
"I've never considered a president's party or identity" in confirming a Supreme Court justice, Collins said, adding that she confirmed President Obama's Supreme Court picks Justice Elena Kagan and Justice Sonia Sotomayor.
Collins said she had met with "thousands of my constituents", noting that both supporters and opponents of the judge had given her their opinions in the days since Ford came forward to accuse Kavanaugh of sexual assault. They argued Friday that Democrats would never be satisfied with any investigation, and they say that it is the Democrats who are trying to undercut the legitimacy of the Supreme Court.
"The facts presented do not mean that Professor Ford was not sexually assaulted that night or at some other time but they do lead me to conclude that the allegations failed to meet the more likely than not standard", she said.
A fuming Kavanaugh strode into the same packed hearing room that afternoon and said he, too, was "100 per cent" certain the incident had not occurred.